Can You Take Melatonin Together With CBD and Mushrooms? - Cannabotech CBD Questions & Answers

Can You Take Melatonin Together With CBD and Mushrooms?

Melatonin, CBD, and functional mushrooms are all being used as natural sleep aids. Read here to find out if you can take them together and how to do so.

Joel Taylor - writer and editor for Cannabotech
By Joel Taylor
Kelli Harris
Edited by Kelli Harris

Updated April 14, 2023.

In recent years, many people have been looking towards natural sleep aids in the form of melatonin, cannabidiol (CBD), and functional mushrooms. Although they have many of the same benefits for sleep, they don't operate with the same mechanisms, but does that mean they are safe to take together?

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Do CBD and Functional Mushrooms Interact With Melatonin?

Melatonin is a hormone produced naturally in our bodies that regulates our circadian rhythm (sleep schedule), but it can also be taken as a supplement to assist in a poor sleep schedule or other sleep issues.

According to, there are no listed interactions between melatonin and CBD, and there is a lack of research into the interactions between mushrooms and other medicines. However, does suggest that individuals mixing melatonin with CBD should be cautious of the following side effects:

  • Sedation
  • Lack of concentration
  • Impaired judgment and thinking

That being said, there is abounding anecdotal evidence to suggest that individuals who have combined these products have had improved sleep quality.

How to Take CBD, Mushrooms, and Melatonin Together

Many products contain melatonin, such as supplements, tablets, gummies, and even tinctures. It's up to your personal preference to decide which method you prefer.

At Cannabotech, we do not use melatonin in our products, but we have combined the therapeutic powers of CBD with functional mushrooms in our unique M2CBD formula. Take a look at our online store for products to help you with stress, anxiety, sleep issues, and more.

As discussed in our post: Melatonin vs. CBD and Mushrooms, melatonin is better taken a few hours before your regular bedtime to reduce sleep latency, whereas our M2CBD products work by improving relaxation and reducing stress, thus making them suitable for use whenever your life is at its most stressful.

Should You Take Cannabotech Products With Melatonin?

Although the anecdotal evidence suggests that CBD and functional mushrooms are safe to mix with melatonin, caution should always be exercised when adding new supplements to your life. Whether you choose to take them simultaneously in the evening before bed or space your doses out is up to you. There is no right or wrong answer for this, as it is primarily up to you to decide what works best for your situation. Just be sure to watch out for side effects and stop if you experience any.