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Functional mushroomsUsing Lion’s Mane for Multiple Sclerosis: 5 Restorative BenefitsMultiple sclerosis (MS) is a chronic autoimmune disease with no current cure that affects the brain and nervous system and can impact all aspects of your life. All treatments for multiple sclerosis involve symptom management, and emerging research on the benefits of Lion's Mane mushrooms suggests a variety of potential benefits that may help relieve symptoms.
The most common symptoms of multiple sclerosis which treatment is sought after include:
FatigueTingling and numbnessMobility issuesSpasmsStiffness or weaknessInsomniaPainDepressionAnxiety
That being said, read on to learn more about Lion's Mane.
What Is Lion's Mane?
Lion's Mane is a large white fungus with tendrils that give it a shaggy appearance resembling a mane. It is used in cooking due to its pleasant taste, but has also been a prominent ingredient in alternative medicine for centuries, especially in Asia. (1).
Lion's Mane may promote nerve growth factor (NGF) which is essential in maintaining neurons in the brain and promoting new growth. In multiple sclerosis, the body attacks the myelin, the protective covering that surrounds our nerves. NGF specifically helps to encourage the growth and repair of neurons.
With this in mind, the following features of Lion's Mane may bring some relief to multiple sclerosis patients.
» Learn more: The Beginner’s Guide to Lion’s Mane Mushrooms
1. Repairs Nerve Damage
Nerve growth factor is essential for the maintenance of neurons and the brain (2). Brain-derived neurotrophic factor (BDNF) is a protein that supports the maintenance and repair of neurons. Research suggests that Lion's Mane may have neurotrophic properties that can promote the growth and repair of neurons in the brain, similar to NGF and BDNF (3).
Additionally, some research also suggests that lion's mane may decrease neuronal damage from the formation of amyloid-beta plaque that accumulates in the brain in Alzheimer's disease.
2. Improves Myelination Processes
One of the most troublesome symptoms of myelin degeneration is neuropathic pain (pain originating in any areas of the nervous system, including the peripheral nerves, spinal cord, and brain). Neuropathic pain can be triggered by usually non-painful stimuli and is either ongoing or stabbing intense pain (described as like electric shocks).
Lion's Mane may help with this because, as discussed above, nerve growth factor may help to repair myelin. Additionally, Lion's Mane may exhibit analgesic (pain-relieving) properties (4).
» Looking for an effective natural remedy for pain? Try our Unwind Drops and Unwind Muscle Rub
3. Regulates the Immune System
Medications for MS are often designed to reduce the activity of an overactive immune system and are thus called "immunosuppressants". While this works, they also tend to lower overall immunity, which may cause the patient to become more susceptible to other infections and diseases.
Lion's Mane is regarded as one of the best functional mushrooms for the immune system and may help regulate immune function by acting on the gut microbiota (5), which can help reduce symptoms of MS and modulate the off-balance caused by immunosuppressant drugs.
» Need an extra boost to your immune system? Take a look at our Immunity Drops and Immunity Support supplements
4. Provides Anti-Inflammatory Actions
Multiple sclerosis is considered an inflammatory disease (as are most autoimmune diseases), and so inflammation plays a large role in many of the symptoms.
Research suggests that Lion's Mane may drastically decrease inflammation (6). There have been several positive lab and animal studies that show a positive correlation between a decrease in overall inflammation and a similar decrease in the symptoms of MS.
5. Improves Mental Health
Many people with MS have cognitive symptoms (like difficulty thinking clearly and problems with short-term memory) as well as symptoms of depression and/or anxiety. Research suggests that Lion's Mane may assist with the following cognitive issues:
Memory (7)Depression and anxiety (8)Brain fog (9)
» Boost your mood with our range of Mood Support products
Consider Other Alternative Remedies
Lion's Mane may have a positive impact on a variety of symptoms caused by multiple sclerosis, all of which can contribute to a higher quality of life. While the amount of research is increasing, much of the current studies have been based on animals. More human research is necessary before we can fully describe the benefits of using Lion's Mane mushrooms as an adjunct treatment for people who suffer from multiple sclerosis.
That being said, the risk of potential side effects from using Lion's Mane and other functional mushrooms is reportedly low for most individuals. Though you should always consult your doctor before trying new supplements, you may see a benefit from combining Lion's Mane and other functional mushrooms with a variety of alternative therapies. Read our M2CBD formula to learn more.
LegalityIs It Legal to Grow CBD Plants in the UK in 2022?When people talk about growing cannabis plants specifically for CBD, there must be a distinction drawn between hemp and marijuana. Although both plants are technically the same species, cannabis, the legally defining difference between them is that hemp plants contain less than 0.3% tetrahydrocannabinol (THC), which is the psychoactive component of cannabis that makes it illegal, while marijuana plants contain more than 0.3% THC.
Technically, CBD can be derived from both hemp and marijuana plants, but does that mean that either of them is legal under the UK laws in 2021? This article looks at this particular question.
Can You Grow Hemp at Home in the UK?
The bad news on this topic is that it doesn't matter what kind of cannabis subspecies you intend on growing. All varieties are labelled as illegal substances according to the Misuse of Drugs Act of 1979, irrelevant of the amount of THC they contain. Basically, all varieties of cannabis in the UK currently have the same label of illicit "weed", and growing weed is definitely not legal under UK law in 2021. If you're just an average person wanting to grow some hemp, it doesn't matter how many cannabis plants you're intending to grow or what their THC concentrations will be, you will be doing so illegally in the UK.
It doesn't matter whether you are wanting these plants for personal use or if you are growing them to sell. If you are caught growing cannabis, you could be sentenced to up to 14 years in prison, and/or receive a fine. Even though CBD in and of itself is legal in the UK, and can be imported without much difficulty, cultivation of plants intended for CBD manufacture is difficult for businesses, and nigh on impossible for the average person.
Growing Industrial Hemp as a Business
UK companies can apply to the British Home Office for a license to grow industrial hemp. The license is called a Controlled Drug Domestic License and only permits you to grow low-THC cannabis (industrial hemp) for harvesting plant fiber and seeds. The license does not permit you to harvest hemp flowers that contain a high concentration of CBD and does not permit you to extract CBD. In other words, the license does not allow you to "make" CBD.
It's a pretty bizarre law that doesn't really make sense to a lot of people. Even if you do want to apply for a hemp growing license, it's not as simple as getting registered in the UK and then growing hemp in your backyard. There are specific requirements that need to be met before you can even think of applying, and even then, it's not a guarantee.
CBD Growing License in the UK
There are specific requirements that need to be met before you can even think of applying for a license to grow industrial hemp, and even then, it's not a guarantee. When applying for a license to grow CBD plants indoors or outdoors, companies have to submit numerous documents, pay fees, and then you might just be awarded a license valid for a few years, whereupon you'll have to reapply.
Applying for a Home Office license to grow medical marijuana as a business is a much more complex (and virtually impossible) procedure. As of 2021, only two UK companies are licensed to grow pharmaceutical-grade cannabis.
How to Get an Industrial Hemp Growing License in the UK
If you are hellbent on growing industrial hemp in Britain, here is a step-by-step process of what you'll have to do to make it so as per the UK government regulations.
Undergo a Disclosure and Barring Service check to prove that there is no criminal activity on your name. You can find a form for this here.Pay an application fee of £580 for new applicants, or £326 for a renewal. Additionally, if a compliance visit is required, the fee will be £1,371.Submit your application form online. Aside from this, the documents required on your part encompass everything including:
i. Personal information and contact details.
ii. Plot details such as location, size, etc.
iii. Type of seeds you intend to plant with the specific variety listed and the THC content.
iv. Verification that this particular seed is an approved type.Obtain your licensing number and wait 4-6 weeks to be approved or denied.
Things to Note About Growing License Requirements
Aside from the difficulty in actually applying for the growing license, there are a bunch of further requirements you have to meet in order for your license to be valid and remain so.
Your crops have to be grown away from schools and public rights of way or vehicular access.If your site changes in the future, you have to inform the home office in advance.The license is technically valid for three years.Holders of a multi-year license need to submit an Annual Licence Review Statement at the start of each growing season. As part of this process, you are required to provide details of the records you have kept for the previous growing season relating to cultivation areas, sowing details, and yields.If you rent the land, the requirements for the license are on your behalf and not the land owner's. Additionally, each location you intend to grow at must be separately licensed.You must inform the local authorities that you intend to grow industrial hemp on your land, even if your application is approved.
Is It Worth It to Grow Industrial Hemp?
The advantage to wanting to grow industrial hemp as a business is that the process itself is easy and hemp is very low-maintenance, which can be profitable if you can get by the outrageous requirements to do so legally. However, if you are simply an individual intending to grow a few CBD plants at home for personal use or as a side business, it is basically impossible under the current laws.
It is likely that things will get better in the future as laws are amended, but this is the current reality for all prospective growers in the countries that make up the UK in 2021. The law doesn't differ between England and other countries for now, unfortunately.
Functional mushroomsWhat Is the Best Time of Day to Take Lion’s Mane?Lion's Mane mushrooms are often touted for the surprising number of potential health benefits that they present. From improving your cognitive function to reducing oxidative stress, it seems that there is a supposed benefit to every situation. But if these mushrooms can supposedly reduce fatigue to give you an energising boost as well as battle insomnia to improve the quality of your sleep, when should you take Lion's Mane?
Does the Form of Lion's Mane Matter?
Essentially, the form of Lion's Mane doesn't make a difference to the benefits you'll experience other than the concentration of the product that you're consuming (assuming that the product has been properly prepared to have the maximum potential bioavailability). So, whether you are taking powdered Lion's Mane mushroom extract in the form of supplements or cooking the fresh mushrooms into food, as long as the concentrations are the same, the benefits will follow suit.
The only factor that could determine a change in the form of Lion's Mane that you decide to take is personal preference. Some people enjoy the taste of Lion's Mane and might want to incorporate them into a meal. However, fresh Lion's Mane isn't the easiest thing to find, and some people prefer the ease of swallowing a tablet over having to cook a meal.
» Result of 10 years Lion's Mane research: Relax CBD drops by Cannabotech
How Quickly Does Lion’s Mane Take to Work?
One factor that plays a part in determining the optimum time of day to take Lion's Mane is how long it takes to feel the effects. If they're instantaneous, then it should be alright to take Lion's Mane before bed, but if they take longer to work, then it might be better to take them in the morning.
Unfortunately, the problem with this question is that the answer is totally different to what you might expect. The benefits of Lion's Mane don't happen immediately after the substance has been digested in the way that pharmaceutical drugs work. They happen as a gradual accumulation over a longer period of time. Although you may experience some minor initial improvements in focus, it's more likely that you'll have to wait a few weeks before you start experiencing these benefits.
Should You Take Lion’s Mane in the Morning?
Many people agree that the morning is the best time of day to take Lion's Mane. Despite the fact that Lion's Mane mushrooms may help with sleep, this effect is primarily due to the mushroom's ability to help your body regulate your circadian rhythm, as well as a decrease to oxidative stress and inflammation, and not that the mushrooms necessarily make you sleepy.
Instead, most of the health benefits of Lion's Mane are understood to be related to cognitive function and brain health, leading to improvements in memory and focus. This means that the isolated benefits you experience from that particular dosage of Lion's Mane would be best utilised in the morning to reduce brain fog throughout the day, which will then follow into a night of better quality sleep.
Can You Take Lion’s Mane At Night?
Even though the general consensus is that you will benefit the most from Lion's Mane mushrooms if taken in the morning, that's not to say you can't take them in the evening as well. Lion's Mane may improve brain fog and cognitive functioning, but it doesn't delay or prevent sleep in the same way that caffeine or other stimulants do.
If the primary reason for wanting to take Lion's Mane is to combat sleep issues, then you should be alright to experiment with taking it before bed and seeing how it affects you in the long term.
» Check out Cannabotech's Lion's Mane-infused Beauty Sleep Drops
How Often Should You Take Lion’s Mane?
After discussing the best time of day to take Lion's Mane, the final thing you have to consider is how often you should be taking it. Since the benefits are meant to accumulate over time, experts recommend taking this supplement daily for the best possible results long-term.
And, since the risk of experiencing side effects from Lion's Mane mushrooms is quite low and that they appear to be very safe, you have some leeway to experiment and determine the best time of day that works for you. Everyone is different, so your results and optimal method won't be completely identical to the next person.
LegalityCBD Laws In The UK: What You Need To Know Before You Purchase CBDCannabidiol continues to take the UK by storm. With its health benefits becoming broadly known and acceptance gaining traction, this trajectory is expected to continue. According to the Global Cannabidiol Market Report, this worldwide industry will explode to £9.72 billion by 2028. That’s a 21.2% compound annual growth rate. The Brits continuously revise CBD laws in the UK to support this market growth as new information arises.
But marijuana has been illegal here since 1928. As CBD comes from the cannabis plant, questions still remain in the community. You might have several yourself.
For example:
What do CBD laws in the UK actually look like?Will I risk a positive drug test if I eat an edible?Does CBD have the same effects as tetrahydrocannabinol (THC)?Am I breaking the law if I buy, consume or apply CBD oil?
These questions are important to answer. Clarity empowers appropriate action. So in this guide, you’ll discover what you should know about CBD laws.
CBD laws: European Union versus Brexit plans
As reported in The Guardian on November 20, 2020, according to EU law CBD is not a narcotic drug. The European Court of Justice came to this determination as CBD “… does not appear to have any psychotropic effect or any harmful effect on human health.”
Yet, different countries have different rules, leading to a grey area for controlled substances. This makes imports and exports tricky because red tape is ample and the rules are in flux.
The United Nations, WHO, EU and the USA appear to be modifying their CBD laws. This is sensible given the benefits that this incredible, safe compound can deliver. Now, post-Brexit UK plans to follow suit.
Here’s what you need to know.
CBD Laws in the UK: Is CBD Legal?
Yes, CBD is legal to purchase, possess and use in the UK as long as it has either no THC or a low THC content (under 0.2%), is made using an EU-approved industrial hemp and is marketed in full compliance with existing regulations.
Note: This is only the case for CBD. At Cannabotech, we are sometimes asked if THC oil or cannabis is legal in UK? No, it’s not at the time of writing this article.
CBD Classification: How Has the Landscape Changed?
While CBD is safe and non-intoxicating, it has not always been regulated accordingly. For years it was thrown in with THC and cannabis. This historically meant gaining access to CBD was banned under cannabis laws in the UK.
Let’s look at its history…
Misuse of drugs act 1971
Cannabis is classified as a Class B controlled drug by the Misuse of Drugs Act 1971. That meant the parliament considered it less harmful than Class A, but more so than Class C drugs.
Misuse of drugs regulations 2002
In 2001, though, a review recommended downgrading the classification of cannabis. The advisory council tasked with this investigation concluded that “The classification of Cannabis as a Class B drug was disproportionate both in relation to its inherent toxicity and to that of other Class B substances.”
Home office licensing for CBD production
But all cannabis isn’t created equal. The Home Office differentiates between cannabis cultivars with a high or low THC level. Then license accordingly.
Gov.Uk states that licences can be issued to grow plants with low THC content for the “production of hemp fibre for industrial purposes or the obtaining of seeds which are then pressed for their oil.”
Licences only allow for the use of non-controlled parts of the plant for defined commercial purposes.Stock must be grown from approved seeds only; ones that contain 0.2% or less THC content.
Note: The 0.2% THC is the maximum to remain within the legal limit. By seeking products manufactured by UK-regulation approved, you ensure you stay legal and safe. We adhere to all CBD laws in the UK so you can gain access to premium products, worry-free.
World Health Organisation (WHO)
Presented in 2018, WHO’s CANNABIDIOL (CBD) Critical Review Report made statements based on the best available evidence. While this doesn’t impact CBD laws, the findings are important. These include:
CBD does not exhibit any potential for abuse or dependenceCBD is well toleratedCBD displays a good safety profileThere is no evidence of “any public health-related problems associated with the use of pure CBD”
Regulatory Status and Rules Related to CBD Products Sold in UK
CBD is safe, well-tolerated, and non-addictive.
It’s not surprising that the Home Office has said, “CBD as an isolated substance, in its pure form, would not be controlled under the MDA 1971 / MDR 2001.” In short, CBD UK law states this compound is legal.
But extracting this compound in isolation is not easy. That’s why CBD laws aren’t as simple as might first seem reasonable.
Tetrahydrocannabinol, as we’ve mentioned, is a controlled drug.
Since both THC and CBD exist within cannabis, there is a chance of cross-contamination within products. Regardless of intention, THC at levels above 0.2% means a CBD product crosses the threshold into a controlled substance.
As such, CBD manufacturers are required to secure and hold an approved license for their products.
In 2019, CBD extracts were confirmed to have what’s called “novel food status.” For food businesses that sell CBD products, this certification is the only route to compliance in the UK. As per food, cosmetic producers must be hyper-cautious with THC. In the UK, cosmetic ingredients must contain no controlled substances. In the case of cannabis, that means no THC.
Governing Bodies and Individual Rules
A range of products are available on the market, with each type having particular governing bodies and regulations.
The Medicines and Healthcare products Regulatory Agency (MHRA) is responsible for consumables. This includes CBD edibles, tinctures, supplements, and oils– anything consumed. You can find out more information here.The Cosmetic Toiletry and Perfumery Association (CTPA) offer greater insight into CBD-containing cosmetics. You can read more here. The legality of CBD flower and CBD bud in the UK (cosmetics) is a grey area nonetheless. A court ruling subject to interpretation, greater clarification will come with time and further legal challenge.Then there is the European Food Safety Authority (EFSA (EU)) and The UK Food Standards Agency (FSA). The EFSA (EU) defines the novel food classification as covering a food “that had not been consumed to a significant degree by humans in the EU before 15 May 1997, when the first Regulation on novel food came into force.”
To meet this classification there are several factors that must be adhered to:
Firstly, the food must be safe for consumers.Secondly, it must be correctly labelled and free from misleading content.Thirdly, if meant to replace another food, the novel food must not lead to nutritional disadvantages. Due to its recency, foods containing CBD are categorised and regulated as a novel food.
In the UK, the FSA set a deadline of March 31, 2021, for companies to submit valid novel food applications. Those who have done so can continue to trade until the results of toxicology studies are returned. The assessment considers THC and CBD. If THC is higher than the allowable 0.2%, novel food registration will be denied.
With so much to consider in regard to CBD laws in the UK, how can you get what you need while remaining safe and legal?
How to Stay Safe and Legal With CBD in the UK
The Takeaway
CBD just got supercharged- banner gif with mushrooms and cannabis
CBD is completely legal to purchase and use in the UK as long as it contains under 0.2% THC and was produced by approved industrial hemp per the Misuse of Drugs Act. This means that marijuana derivatives, which typically contain more THC than CBD oil, are not legal to purchase, use or possess.
To ensure you gain the benefits of cannabidiol while staying on the right side of CBD laws in the UK, purchase only from a reputable store with UK registration. This way you can enjoy the beneficial properties of CBD without concern for breaking UK or EU law.
Cbd discussionsHolistic Treatments for Polymyalgia Rheumatica (CBD Oil and Others)Polymyalgia Rheumatica (PMR) is categorised as an inflammatory condition that leads to joint pain and stiffness, commonly affecting individuals older than 50. It is difficult to diagnose, and currently impossible to cure. The best pharmaceutical treatments for the condition involve combating the symptoms with low-dose corticosteroids, which is problematic as long-term use of corticosteroids can lead to osteoporosis.
Recently, individuals are turning to various alternative treatments and natural remedies in an attempt to help symptoms of PMR holistically, which will be covered in this article.
What are the Best Pain-Relief Treatments for Polymyalgia Rheumatica?
Choose a Healthy Diet
Although a healthy diet may not fix the problem outright, certain foods can definitely worsen the symptoms of PMR. When choosing what foods you should eat, consider sticking to the following guidelines:
Anti-Inflammatory Foods such as nuts, fruits, leafy greens, whole grains, and green tea can contribute to a decrease in inflammation throughout the body.Foods rich in Calcium and Vitamin D, such as soybeans, spinach, cheese, fatty fish, eggs, and mushrooms can help maintain good bone health and counter the negative effect of steroids and corticosteroid medicines.Omega-3 Fatty Acids obtained from fish, seeds, and leafy greens can help counteract the immune system's further production of inflammation.
In addition to these, you should stay away from foods that are deep-fried or contain poor-quality vegetable oils, refined carbohydrates and sugars, alcohol, and red meats.
Take Supplements
If certain foods are unattainable, they can be replaced with supplements in order to give your body the necessary nutrients that it needs.
Consider Alternative Medicines
Traditional Chinese Medicines have been reported to have varying effects in the holistic treatment of rheumatic conditions.
Corydalis (Yu Jin) contains a pain-relieving compound called dehydrocorybulbine (DHCB), and Curcumae (Jiang Huang) has been noted to reduce chronic inflammation.Chinese massages have been known to free up stiff and sore shoulders (a common symptom of PMR), promote vigour and strength, and soothe pain.Acupuncture has been associated with relieving pains associated with arthritic and rheumatic conditions.
Using CBD Oil for Polymyalgia Rheumatica
Although CBD oil may not directly treat PMR, certain products can help with certain symptoms as there is scientific evidence to support the theory that CBD has anti-inflammatory and pain-relieving properties.
CBD oils and tinctures can be taken to reduce general inflammation throughout the body over a longer period.CBD balms and creams can be applied topically to particularly inflamed or painful areas.
Can CBD Be Taken in Conjunction With Corticosteroids (Prednisone)?
CBD interacts with many drugs, and, unfortunately, corticosteroids are one of the most prominently noted. CBD and prednisone both are potent inhibitors of the cytochrome P450 enzyme CYP3A. Taking them in conjunction could lead to a decrease in the clearance of the corticosteroid, which is a measurement of the volume of plasma from which a substance is completely removed per unit time.
This interaction is potentially dangerous as it could lead to increased side effects from prednisone, namely, among others:
Weight gainMuscle weaknessLower resistance to infectionOsteoporosisAn onset of, or worsening of, diabetes and hypertension.
A Final Thought: Can CBD Oil Replace Prednisone?
Due to the potential for increased side effects, it is not advised that CBD oil and prednisone be taken in conjunction with one another. Since corticosteroids have the potential to cause osteoporosis in the long term, CBD may be considered as a potential replacement in the future, but there is currently no scientific evidence to support this theory.
What this means for you is that you should consult directly with your doctor before deciding to end your medication as they can give you more insight and advice on the topic.
Functional mushroomsThe Secret to Radiant Skin: 8 Turkey Tail Mushroom BenefitsThe functional mushroom Trametes versicolor is commonly called Turkey Tail due to its striking layers and colors. With potent antioxidants and other powerful compounds, Turkey Tail mushrooms are a superfood with numerous potential health benefits. It may improve your gut health, boost your immunity, and even possess some anti-cancer properties.
One of the most prominent benefits of Turkey Tail mushrooms is their potential improvements to skin health.
1. Anti-inflammatory Properties
Turkey Tail mushrooms, alongside most other mushroom species, appear to soothe inflammation in your body, which can be extremely beneficial to the symptoms of inflammatory skin conditions like eczema and psoriasis (1).
» Learn more: Treating Inflammatory Psoriasis With CBD and Functional Mushrooms
2. Anti-ageing Properties
The build-up of oxidative stress over time causes and exacerbates wrinkles as free-radicle damage breaks down the collagen, elastin, and other proteins that keep your skin tight and looking full. When these proteins are damaged, your skin sags and struggles to regenerate, leading to wrinkles and other signs of damage, such as sun spots.
The flavonoids and phenols in Turkey Tail mushrooms appear to reduce oxidative stress and inflammation, essentially having anti-ageing effects (2). Flavonoid antioxidants, such as quercetin in Turkey Tail mushrooms, also boost immunity by stimulating the release of protective proteins (3).
These mushrooms are used in cancer treatments since they have antitumor properties. Researchers have noted that a daily dosage of turkey tail mushrooms decreased tumor size in their test subjects (4).
Do Turkey Tail Mushrooms Really Reduce Wrinkles?
Yes, it would appear that Turkey Tail mushrooms can help reduce the appearance of wrinkles.
Functional mushrooms such as Tukey Tail contain phenolic veratric acid, an antioxidant compound that helps reduce wrinkles. Its photo-protective effects shield you from the molecular damage caused by sunlight (5).
» Keep your skin young with a personalised anti-ageing skincare routine
3. Turkey Tail May Brighten Your Skin
Turkey Tail mushrooms are gaining popularity as a natural ingredient in skincare products as healthy skin is widely regarded as appearing brighter and free of blemishes. This fungus is packed with antioxidants that slow down signs of ageing and help you retain a more youthful and bright appearance while also repairing cellular damage and inflammation resulting from oxidative stress.
4. Turkey Tail Can Help Moisturize and Hydrate Your Skin
If your skin is dry or damaged, then Turkey tail mushrooms are what you need. The quercetin in turkey tail mushrooms reduces water loss and helps maintain skin hydration by restoring skin barrier function. Quercetin also helps restore connective tissue cells in the skin which positively influences the secretion of collagen and elastin. This rejuvenates your skin and keeps it looking healthier and younger.
Additionally, Turkey Tail mushrooms also contain high levels of beta-glucans that have humectant properties (a substance that draws water into the skin).
» Suffering from psoriasis? Discover how to avoid triggering psoriasis flare ups
How to Use Turkey Tail Mushrooms for Skin Health
There are many ways to use Turkey Tail mushrooms, such as a simple decoction using the fresh fungus steeped in water and consumed as a tea. However, this mushroom is also available as an extract combined with other therapeutic components, such as capsules, lotions, and tinctures.
» Browse our store for more Turkey Tail-infused products
4 Other Benefits of Turkey Tail Mushrooms
1. Turkey Tail Mushrooms May Stimulate Cognitive Function
Turkey Tail appears to slow the degenerative process of neurotransmitters in the brain due to the accumulation of Acetylcholinesterase (AChE) and free radicals. Steady production of AChE and the presence of free radicals leads to cognitive disorders such as Alzheimer's and dementia. A study published by the Journal of Enzyme Inhibition and Medicinal Chemistry found that H2O extracts of Turkey Tail mushroom had the benefit of inhibiting AChE and exhibiting anti-radical properties (6).
2. Turkey Tail Mushrooms May Inhibit Cancer Production
As it turns out, there is a growing body of research on Turkey Tail mushroom's cancer benefits.
Firstly, studies have shown that Turkey Tail's polysaccharides appear to inhibit cancer cell growth in vitro by stimulating cytokine response, as well as having direct anti-tumour properties outside of the immune system effects (7). Furthermore, another study found that Turkey Tail mushrooms activated and increased the lymphocyte count, natural killer cells, and specific T cells against breast cancer (8). It may also increase the efficacy of other cancer treatments.
3. Turkey Tail Mushrooms May Boost the Immune System
Caution needs to be exercised by those wanting to use Turkey Tail with autoimmune diseases as it is unclear whether the fungus is immunomodulatory or immunostimulatory. Evidence concluded that Turkey Tail mushrooms benefit gut health as they act as a prebiotic that can stimulate the production of good bacteria in the gut, not only assisting the immune system but also potentially cancelling out a major side effect of antibiotics (9).
The same study also concluded that Turkey Tail mushrooms appear to be anti-bacterial as they suppressed the growth of E. coli and Shigella.
» Discover how functional mushrooms boost the immune system
4. Turkey Tail Mushrooms May Lower Blood-Sugar Levels
Studies have found that one of the functional benefits of Turkey Tail mushroom extract was to lower glucose levels in the blood (10). This alone presents several further benefits:
Athletic performance and sleep quality
High blood glucose (a common symptom of diabetes) can contribute to feelings of fatigue and lethargy. The same study found that a consequential result of lower blood glucose levels in mice as a result of Turkey Tail improved their athletic performance. It stands to reason that reducing symptoms of fatigue during wakefulness will help your body modulate your circadian rhythm and stimulate better sleep quality.Diabetes and insulin resistance
The same study listed above also noted that Turkey Tail mushroom extracts "may promote the glucose utilization to peripheral tissues and has a glucose-lowering action," which could be particularly beneficial to diabetes patients and those who suffer from insulin resistance.
Rejuvenate Your Skin With Functional Mushrooms
If you are unsure whether you are predisposed to any mushroom allergies or the side effects of Turkey Tail, or if you simply would like more advice for your particular situation, chat with a doctor before supplementing your diet. Not only can they recommend dosages, but they can also explain the best ways to take Turkey Tail mushrooms.
However, Turkey Tail and other functional mushrooms may be a great way to bring some life to your skin.
» Need more help? See our anti-ageing skincare tips
Other medicationsTaking CBD Oil With Antidepressants: Effectiveness and RisksDepression can manifest in many different forms, though it is usually characterised by mood problems, constant feelings of sadness, and loss of interest in previously enjoyed activities. It is rarely the result of a single event but rather as the combination of multiple factors, and symptoms can range from mild to severe.
Treatments for depression can be achieved by psychotherapy or with the use of medicines, though the most benefits are experienced with a combination of the two.
Recently, researchers are looking into CBD as a potential treatment for depression due to its claimed anxiolytic and mood-boosting effects. This article will look at the efficacy of using CBD as a treatment for depression, as well as the potential risks of using it in conjunction with other antidepressants.
Is CBD Oil Good for Depression?
The nature of this question can only be answered if you address the many different factors that contribute to an overall case of depression. Not all types of depression are the same, and different individuals will manifest different symptoms. Generally, although relatively limited, there is some scientific evidence to suggest the effectiveness of using CBD to treat depressive conditions at their core.
However, there is more evidence to suggest CBD's effectiveness at treating a number of other mental health problems commonly experienced in conjunction with depression. Assisting in the various secondary conditions may indirectly contribute to the management of depression and the lifting of the overall quality of life.
CBD May Be Anxiolytic
Those who suffer from depression commonly also suffer from some form of anxiety, and the same is true in reverse. There is a growing body of evidence to support the belief that CBD exhibits anxiolytic (anti-anxiety) properties in many individuals.
CBD May Reduce Stress and Improve Mood
Mammals have an inbuilt system in their bodies called the endocannabinoid system, which is believed to modulate the central nervous system and maintain homeostasis between physiology, cognition, and emotion. CBD interacts directly with this system, which may suggest why it seems to assist individuals in managing stress levels and improving their general mood.
One of the ways it does this is by changing the way your brain responds to serotonin, a hormone associated with stabilising mood and happiness.
Can Taking CBD Cause Depression?
Currently, there is no evidence (clinical or anecdotal) to suggest that CBD can actually cause depression. Although the side effects of CBD are rare and mild, they usually go away after an individual stops taking CBD. At most, CBD may cause general somnolence and fatigue, but not depression.
Some mental health problems are triggered and exacerbated by THC, the psychoactive component of cannabis. Still, there is evidence to suggest that CBD can help in both preventing these effects as well as helping to reverse them.
Can You Take CBD With Antidepressants?
"Antidepressant" is a blanket term that encompasses a multitude of different products that treat depression through many different mechanisms. However, an important similarity between most antidepressants is the way that they are metabolised by the liver.
The liver is home to a number of different enzyme systems that catalyse (speed up) reactions. Among these are the cytochrome P450 (CYP450) enzymes that are responsible for breaking down many different medications, including antidepressants. CBD is a potent inhibitor of these enzymes, and so there could be interactions with CBD and antidepressants.
What this means is that taking antidepressants with CBD oil would slow the process that these medications are metabolised, which could lead to more of the substance being left in the body at a given time and increasing the potential for adverse reactions or even overdose. It's important to note that the form of CBD doesn't matter as it exhibits the same effects and interactions once it reaches the bloodstream.
Types of Antidepressants and Their Risk Factors
Since antidepressants work in different ways, some present more risk when taken with CBD oil than others.
Selective Serotonin Reuptake Inhibitors (SSRIs)
These are currently the most commonly prescribed antidepressants and work similarly to CBD in the way they prevent the reabsorption of serotonin into the brain, leading to more available serotonin and a related improvement to mood.
The most common SSRI's are:
Citalopram (Celexa)Escitalopram (Lexapro)Fluoxetine (Prozac)Paroxetine (Paxil or Pexeva)Sertraline (Zoloft)Vilazodone (Viibryd)
The reason for SSRIs being the first choice for doctors is that they generally present fewer side effects than other antidepressants. Because of the nature of their operating mechanisms, taking CBD while being on any of the listed antidepressants would present similar effects, as is the case for all antidepressants belonging to a particular drug class.
Serotonin-norepinephrine reuptake inhibitors (SNRIs)
These operate similarly to SSRIs and present the same level of risk, but may work better for some individuals.
Common SNRIs include:
Duloxetine (Cymbalta)Venlafaxine (Effexor XR)Desvenlafaxine (Pristiq)Levomilnacipran (Fetzima)
Tricyclic antidepressants
These work by increasing levels of norepinephrine and serotonin in the brain. They can be highly effective but present much more risk than other antidepressants. As such, they are only prescribed when SSRIs and SNRIs have failed. Common tricyclic antidepressants include:
Imipramine (Tofranil)Nortriptyline (Pamelor)AmitriptylineTrimipramine (Surmontil)Desipramine (Norpramin)
Conclusion: Can CBD Benefit or Replace Antidepressants?
CBD may be more beneficial in the long term than traditional antidepressants. Dopamine, a hormone that regulates habitual behaviour through the brain's built-in reward system, is often the reason that individuals build up dependencies on drugs (pharmaceutical and illicit). Research has shown that CBD use doesn't result in similar dependencies but can exhibit the same degree of antidepressive effects.
Even though there is no definitive evidence that CBD directly interacts with antidepressants, the nature of the way they are both metabolised presents some concerns. Research into the efficacy of CBD as an antidepressant may be promising, and there is a growing body of anecdotal evidence suggesting that CBD could be used to reduce dependency on clinical antidepressants, but this should all be taken with caution.
It's not advised to simply replace prescribed medications with CBD without consulting a doctor. However, it's likely that your doctor could assist you in periodically reducing your dose of antidepressants with the hope of supplementing them with the use of CBD in the long term. Each case must be addressed individually as no two people will have the same results. Despite this, there is some hope that CBD could become a viable treatment for depression in the future.
PainThe Menopause Back Pain Breakthrough: Causes and TreatmentsMenopause signals the end of a woman’s reproductive years. The period is characterised by different symptoms, including hot flashes, joint pain, mood swings, night sweats, sleep disturbances, and vaginal dryness caused by dropping oestrogen and progesterone levels.
Back pain is a common complaint of women transitioning through menopause. While back pain is common among older adults, it is more severe in menopausal women.
Causes of Menopause Back Pain
Changes in Oestrogen Level
Oestrogen plays a critical role in maintaining bone density and strength. As the levels reduce during menopause, it leads to weakening bones and a higher risk of fracture (stress fracture and vertebral compression fracture), leading to back pain. Also, oestrogen regulates collagen production, which supports the body's joints.
» Discover the best natural ways to boost oestrogen
Weight Gain
Lower progesterone levels mean a reduced metabolic rate and a possible increase in appetite. Together with changes in body composition, this may lead to weight gain that increases pressure on the spine, muscle tension, and back pain. Also, excess weight may lead to herniated discs, spinal stenosis, and arthritis of the lumbar spine.
Degenerative Arthritis
Ageing is associated with wear and tear of the joints. In perimenopausal women, wear and tear in the vertebrae over time can also result in back pain.
Muscle Strain and Tension
Hormonal changes can increase muscle tension and tightness, which can increase pain in the back muscles.
Disease Conditions
Conditions like fibromyalgia and rheumatoid arthritis can cause severe back pain. With fibromyalgia, there is widespread discomfort, fatigue, and tenderness in the muscles and soft tissues of the back. With rheumatoid arthritis, inflammation in multiple joints, including the spine, causes extreme pain.
Poor Posture
Weakening muscles with age can contribute to poor posture, which leaves the back without proper support, causing strain and leading to lower back pain.
Muscle Imbalance
Back alignment is maintained by the co-action of the core back and abdominal muscles. When the abdominal muscles are stronger than the back muscles, tension builds and alters the body's alignment, leading to muscle strain and pain.
Treatment Options for Menopause Back Pain
While the treatment of menopausal back pain may vary depending on the underlying cause and severity, here are some common and effective treatment options:
Lifestyle and Dietary Adjustments
This includes the following:
Regular exerciseKeeping a healthy weightGood postureEating a healthy and anti-inflammatory dietEnsuring proper support for the back
» Find joint pain relief with these menopause-friendly exercises
Over-The-Counter Medication
Medications like acetaminophen can help prevent inflammation and relieve mild to moderate back pain.
Physiotherapy
A physical therapy regimen can help improve back mobility and strengthen the back muscles. It can also address postural problems, aid muscle relaxation, and increase flexibility, all of which contribute to reducing back pain.
Hormonal Therapy
Hormonal replacement therapy can help restore oestrogen and progesterone levels and alleviate the problems contributing to the increased risk of back pain.
Relaxation Techniques
Proper rest or sleep can help alleviate pain related to stress and muscle tension. Yoga, meditation techniques, a walk in the park, deep breathing techniques, and journaling can also help.
» Learn more: Stress-relieving tips for adult women
Vitamins and Supplements
Perimenopausal women are at risk for Vitamin D and calcium deficiency, which may lead to muscle spasms and osteoporosis. Taking supplements may help prevent these deficiencies.
Alternative Therapies
Approaches like acupuncture, massage, and chiropractic care may also bring back pain relief, though you should always consult your medical care provider before trying out any alternative therapies.
Surgery
Surgery becomes an option when back pain does not respond to conservative treatment. Surgical approaches include spinal fusion, laminectomy, or discectomy.
Take Action Today
Although menopause may be inevitable, that's no reason to give up and let back pain and other symptoms worsen rapidly. There are many techniques you can follow to begin to alleviate your symptoms, most of which can be carried out in the comfort of your own home and without costly procedures or equipment.
» Not sure where to begin? Find your personalised wellness routine with our quiz
Other medicationsTaking CBD Oil With DiazepamDiazepam, first marketed as Valium, is a class of drug called benzodiazepines and is used to treat anxiety, muscle spasms, and seizures. These are some of the same symptoms that people claim can be helped with the use of cannabidiol (CBD). Logical reasoning might suggest that taking them together would compound the benefits of both, but such is not always the case when discussing medications that directly influence your body's natural state.
With that being said, we can now ask the question: Can you take CBD oil with Diazepam?
Interactions and Effects of Taking CBD and Diazepam Together
The scientific research of interactions between CBD and other drugs is quite clear. Benzodiazepines are enzyme substrates that work by enhancing the effect of a neurotransmitter known as gamma-aminobutyric acid (GABA), which is a type of chemical that communicates either stimulating or calming messages between brain cells.
CBD interacts negatively with most enzyme substrates and causes an increased risk of side effects relating to that substrate. In the case of diazepam, some of the side effects (among others) are:
DrowsinessLight-headednessConfusionDizzinessSlurred speechMuscle weaknessMemory problemsNausea
Taking CBD Oil and Diazepam Together
With the potential for increased risk of side effects due to drug-to-drug interactions between the two substances, it is definitely not recommended that you take CBD products of any kind simultaneously with diazepam (or benzodiazepines of any kind). If you absolutely have to take both, then it's advised that you follow these procedures:
Reduce the dosage of the substrate (diazepam).Avoid taking them at the same time, allowing a few hours in between doses.Monitor consistently for adverse effects and, if you experience any, stop immediately and contact your doctor.
A Final Thought
Although the potential for adverse reactions due to CBD is incredibly low, and the amount needed to overdose on CBD alone is outrageously high, this absolutely does not mean that it is safe in all scenarios. Some individuals are more sensitive to it than others, and the danger increases exponentially when you take CBD in conjunction with many different kinds of medications.
You should always talk to your doctor before including CBD in your life, especially if you are on medication. They will always be willing to help, and even if they don't advocate for CBD themselves, they can still give you some insight into the potential benefits and risks.