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The Endocannabinoid System: How Does Cannabidiol (CBD) Work In The Body?
Cbd discussionsThe Endocannabinoid System: How Does Cannabidiol (CBD) Work In The Body?Cannabis, with its fibrous and active compounds, has been part of human history for millennia. Used as herbal medicine, in a spiritual ceremony, eaten as food, and weaved into paper and linen, the versatility of this fast-growing plant is impressive. Yet, its ability to create a mind-altering high led to a blanket ban. As a consequence, research halted. We still have much to learn but what we do know is impressive and meaningful. There are an estimated 483 different chemical constituents. Of these, 66 fall into the category of cannabinoids; compounds not found except in the cannabis plant. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are two important cannabinoids that have, in recent times, captured the imagination of scientists, health experts and the public alike. It’s about time! The scientific journey began decades ago. Israeli organic chemist and professor, Raphael Mechoulam, uncovered the structure of CBD and THC in 1963 and 1964. In 1980, he and his team published a study in the journal, Pharmacology. They found that CBD had potential as an anti-epileptic drug. The results were staggering, yet the knowledge remained all but hidden; cannabis and its health-giving compounds remained illegal in most countries. Wonderfully this is changing. The CBD cat has pounced out of the medical bag. How CBD works in the body? This begs the question of exactly how CBD works in the body? For the body to remain in balance (homeostasis), our cells must be able to “talk”. They do this via signalling. Instead of engaging in oral communication, each cell contains biological locks. When a key (a chemical or hormone, for example) meets the right lock, magic happens; a process is unlocked, a signal can be sent. This allows a message to be amplified and passed along. Thus, a response can occur. In some ways, it is like a computer operating system designed to make you ‘run smoothly’. Each step triggers the next. Cannabidiol (a “key”) affects the cell’s cannabinoid receptors (the “lock”). In this way, this compound can trigger beneficial responses. But how can a plant compound change the way the body works? This is the perfect question and where things really become interesting! To understand, we must look at the endocannabinoid system or ECS. The endocannabinoid system: What is the ECS and how does it work? While the term endocannabinoid system sounds complex, it simply refers to the cannabinoid system within us. Yes, the human body is organised to respond to cannabinoids. It also produces them! The endocannabinoid system regulates the nervous system. Part of its role is to help the body respond to internal and external insults; it is inseparably tied to your physical and psychological responses. It does this via the lock and key mechanism mentioned above. What makes up the endocannabinoid system? The endocannabinoid system has four parts including: Cannabinoid receptors called CB1 and CB2.Cannabinoids produced by the body (endocannabinoids)Enzymes that either make or break down cannabinoids.Cannabinoid antagonists; chemicals that block these molecules from connecting with their receptors like a basketball player blocking the hoop. Because the receptors and the body’s own cannabinoids offer possible therapeutic effects, let’s look at these two in more detail. The lock: cannabinoid receptors (CB1 and CB2) The receptors of the endocannabinoid system are just like any other: incredibly specific. The key must fit the lock to trigger an action. Cannabinoid receptor one (CB1) is mostly found in the central nervous system; that is, the brain and the spinal cord. It is involved in appetite, coordination, memory, mood, movement, pain, and other functions. Cannabinoid receptor two (CB2) is mostly found in the peripheral nervous system; that is, areas other than the brain and the spinal cord, especially in immune cells. Because of this CB2 may influence the immune system, inflammation, and pain. The key: cannabinoids naturally produced in the body The incredible human body produces two “keys” that fit the cannabinoid “locks”: anandamide (AEA) and 2-arachidonoylglycerol (2-AG). Anandamide, dubbed the bliss molecule, acts as a neurotransmitter; a chemical that enables nerve cells to communicate with each other or tissues like glands or muscles. 2-AG, while being identified, remains somewhat of an enigma. This endocannabinoid appears to regulate the nervous system, protect cells in the brain, and play a role in immune function. Nature’s locksmith: The role of enzymes The body is designed to maintain equilibrium. Too little of one compound and it will work to raise your level. Too much of another and it will work to aid decline. A finely tuned balance is the aim. Enzymes, then, are biochemical catalysts; they enable chemical reactions to occur at a rate designed to support life. Imagine a bath. If it’s too hot, you’ll burn as you slide into the water. If it’s too cold, you’ll begin to shiver. We can think of enzymes as taking control of the taps to ensure the temperature is just right. In terms of cannabinoids, enzymes help to maintain perfect function and balance. What is the role of plant cannabinoids? Humans have, for aeons, believed that Mother Nature provides medicine. Science is finally beginning to investigate, understand and support this notion. The phytocannabinoids — literally “plant” cannabinoids — include cannabidiol (CBD) and tetrahydrocannabinol (THC). Where the latter alters psychological state, it appears CBD can ease discomfort, enhance mood, and modulate nerve and brain function, without the psychoactive effects of THC. Whether from inside the body (endogenous) or outside (exogenous sources like cannabis), cannabinoids provide the key that opens the lock in the form of CB1 and CB2 receptors. This initiates physiological change. This means that external cannabinoids can deliver therapeutic benefits. You can support your body through appropriate supplementation. The Takeaway on the Endocannabinoid System The endocannabinoid system is complex and important. There is still much to learn but what we already know is astounding. This widespread biological network helps to moderate homeostasis so we can remain well. And, nature provides a plant-based mimic. CBD is legal and able to connect with the same receptors that endocannabinoids can. It provides the right key to unbolt the cannabinoid lock. The result? Consuming an appropriate natural compound may benefit your health. It doesn’t get much better than that!
Taking CBD Oil Sublingually (Under the Tongue): Guide, Safety, and Benefits
Cbd discussionsTaking CBD Oil Sublingually (Under the Tongue): Guide, Safety, and BenefitsSublingual application is the process of placing a substance under your tongue. This allows it sufficient time to diffuse through the surrounding tissue and into the bloodstream, which differs from regular oral consumption. This article will discuss all you need to know about using CBD oil sublingually, the benefits, how-to, safety, side effects, as well as some product recommendations. How to Correctly Administer CBD Oil Under the Tongue Though the method of taking CBD sublingually is very specific, it's also incredibly easy. Note that the substance must be held under the tongue as different areas of the mouth have different types of cells that might not be permeable enough for diffusion into the bloodstream. CBD oil needs to be put under the tongue and held for at least 60 seconds to allow sufficient time for the molecules to diffuse across the epithelial cells. This method remains the same regardless of the dosage or the form (oils or tinctures). There is no correct dosage or best time of day to do this as it varies depending on the person and condition being treated, but it stands to reason that higher doses might require more time to diffuse into the bloodstream. When taking higher doses, hold the CBD under your tongue for up to 2 minutes without swallowing to ensure complete absorption. Additionally, it's advised not to take the CBD during or directly after a meal as some of the oil may absorb into the food particles and not into the bloodstream. How Often Should You Take CBD Oil Sublingually? Although it varies, most individuals take CBD oil sublingually once or twice a day, either in the morning or a few hours before bed. Bear in mind you can also take it both in the morning and in the evening, and that you are not limited to these times. However, figuring out how often you should take CBD oil depends on the individual and relates to various factors such as body weight and the severity of the condition. Take Back Control Naturally Whether you're looking to unwind after a long day, manage stress, or improve your sleep quality, Relax Drops by Cannabotech may be just what you need. Contains pharmaceutical-grade CBD oilPacked with 3 types of functional mushroomsNo psychoactive ingredients, 0% THC The Relax Drops are designed to provide a calming and relaxing effect on the body and mind, thanks to their unique blend of natural ingredients and high-quality CBD oil. Benefits of Taking CBD Oil Sublingually Here are some of the biggest benefits of administering CBD oil under the tongue: Increased Bioavailability: Since sublingual application bypasses the metabolic process of digestion, far less of the raw CBD is lost. The term bioavailability refers to how much of a substance can be utilised by the body and differs depending on the method. As for CBD products, the only method with higher bioavailability than sublingual is inhalation.Faster to Take Effect: Similarly to increased bioavailability, bypassing the slow digestion process means that the effects of CBD tinctures taken sublingually can be experienced much faster. Whereas it can take upwards of 30 minutes to benefit from oral consumption of CBD, taking CBD oil sublingually can yield results in only a few minutes.Ease of Use: Not having to prepare the product or inhale smoke and vapour makes sublingual application easier. Just place a few drops under your tongue, don't swallow for a few minutes, and let your body do the rest. Is Holding CBD Oil Under the Tongue Safe? CBD is generally understood to be relatively safe compared to most substances. Taking CBD oil sublingually doesn't increase the risk of any CBD-related side effects compared to oral consumption. Let's take a look at some commonly asked questions: What Happens if You Accidentally Swallow CBD Oil? Accidentally swallowing CBD oil won't pose any risks to your body. However, once you swallow the substance, you are no longer taking it sublingually. Instead, you are consuming it, which means that it will have to be metabolised through your digestive system before your body can utilise it. Although this isn't dangerous, it does mean decreased bioavailability and slower onset of effects. Should You Take CBD With Food or an Empty Stomach? Since sublingual application bypasses the digestive system entirely, there's no need to worry about taking it with food or on an empty stomach. Neither will change the results. Can You Drink Water After Applying CBD Oil Under the Tongue? After the total time is up, the process is complete, and the CBD has diffused into your bloodstream. Drinking water or eating food now won't prevent the CBD from working, so you are free to do as you please. However, you might want to give it a few more minutes before drinking any water just to ensure that your body manages to absorb as much CBD as possible. Side Effects of Taking CBD Orally and Sublingually Aside from the general side effects of CBD, the potential side effects related to sublingual application are mild and uncommon, though some people have reported the following: Slight numbness under the tongueAversion to the texture of CBD oilAversion to the taste of CBD tinctures Sublingual CBD Myths Busted Despite the low risk of mild side effects associated with CBD, there are some unfactual claims about certain supposed side effects that simply aren't true. The most popular ones are: "CBD stains your teeth" This myth comes from the associations between smoking and stained teeth. Make no mistake, smoking tobacco products and cannabis alike will definitely stain your teeth over time, but simply putting a few drops of CBD oil under your tongue will not turn your teeth yellow. "CBD makes your breath smell" This myth likely also comes from the associations between smoking and bad breath or potentially from the relatively unpleasant taste of CBD oil. However, bad breath is caused by odour-producing bacteria in the mouth. On the other hand, CBD has antibacterial properties that can actually aid bad breath. If you're still worried about the potential effect of CBD oil on your dental hygiene, simply take it before bed or in the morning and brush your teeth afterwards, as this will not impact the effectiveness of the product. The Sublingual Route: Taking CBD Oil Under the Tongue is Safe and Effective Taking CBD tinctures sublingually is far more advantageous than oral consumption of tablets or oils. With its higher bioavailability and speed while not presenting any higher risk of side effects, sublingual application is one of the best and most effective ways of taking CBD. However, before including CBD in your lifestyle, you should consult your doctor, especially if you are on other medications.
CBD Benefits: How This Natural Compound Promotes Health and Wellness
Cbd discussionsCBD Benefits: How This Natural Compound Promotes Health and WellnessAre you interested in creating a vibrant body and mind? Have you begun to question the veracity of popular health advice? Or maybe you’ve heard people talking about CBD benefits for their wellness routine? CBD, or cannabidiol, is a natural compound found in the cannabis plant. While its structure and stereochemistry were explained in 1963, its ties to marijuana led to a distinct lack of research worldwide. Yet, recent legalisation has lead to a flurry of interest, availability, and research. Thankfully! Why? As the decades whizz by, ill-health continues its upward trajectory. Levels of cancer, cardiovascular disease, chronic lung diseases, and diabetes continue to soar. In fact, the chances that one of these four will “take you out” is estimated at three in five. To make matters worse, around one-third of our population live with multiple chronic conditions. Clearly what we’re currently doing isn’t working! But death is not the only concern. Ongoing illness brings with it challenges including mobilityemploymentmaintaining a social lifeenjoying leisure activitiesand more. Then there are the ongoing stressors, fatigue, mood disorders, and other health problems that come with the endless hustle and bustle of life. Present-day living, for most people, contributes both to disease and a life lived “less than”. People are sick and tired of being sick and tired. Through either personal struggle or watching loved ones suffer, many have decided to switch their focus and adopt a wellness routine. To flourish rather than flounder. To thrive rather than merely survive. This is where CBD for wellness routine vigour comes in… How CBD benefits your wellness routine? The therapeutic prescription of cannabis dates back millennia. Ancient Chinese texts report benefits for headache and pain, mood and insomnia, menstrual irregularities and anaemia, muscle tension and convulsions. But how might this be at all possible? Cannabidiol works through a biological network called the endocannabinoid system, or ECS. As we explain in our article, The Endocannabinoid System: How Does Cannabidiol (CBD) Work In The Body?… For the body to remain in balance (homeostasis), our cells must be able to “talk”. They do this via signalling… When a key [chemical] meets the right lock [receptor], magic happens; a process is unlocked, a signal can be sent. This allows a message to be amplified and passed along. Thus, a response can occur. In the ECS, the “keys” are cannabinoids like CBD. When a cannabinoid binds to its matching receptor, regulation of a range of bodily functions occurs… This may have benefits for sounder sleep, a healthy appetite, enhanced memory, optimal fertility, pain relief, and more. Via this mechanism, CBD produces a range of beneficial changes that may support your health-boosting wellness routine. How CBD benefits the four foundations of wellbeing There are foundation pieces we need to get right to live a healthy life; stress managementsufficient sleepa healthy dietadequate exercise Cannabidiol may help with the first two. And when you’re well-rested and relaxed, the second two become much easier. 1. CBD may help with stress management Oh, the joys of the modern age! If you’re not attempting to multitask or create extra time to finish your to-do list, enjoy! But if you are, welcome! You are not alone. But constantly having the pedal pushed firmly to the metal can be exhausting, overwhelming; yes, stressful! This ongoing pressure can take its toll on your physical and psychological health. Yet, there is hope. A review published in the journal, Neurotherapeutics, found that “Overall, current evidence indicates CBD has considerable potential as a treatment for multiple anxiety disorders.” Cannabidiol may be just what you need to calm nervousness and stress. 2. CBD may support healthy sleep and wake cycles Do you head to bed only to toss and turn? Do you wake during the night, besieged by incessant worries? Or do you rouse to the alarm feeling unrefreshed? Formulate Health’s, Insomnia Statistics UK 2021, found that 36% of UK adults have trouble falling asleep at least once every week. For 20% it’s a daily (or should we say, nightly) struggle. But if counting sheep isn’t working, CBD may offer sleepy respite. A 2019 study titled, Cannabidiol in Anxiety and Sleep: A Large Case Series, found that sleep scores improved within the first month for two out of every three participants. As an added benefit, “Anxiety scores decreased within the first month in [79.2% of people].” It’s not surprising, then, that users report CBD helps to manage self-perceived anxiety, stress, sleep. 3. CBD can be included as part of a healthy diet You may have noticed that CBD has sky-rocketed in the dietary supplement food category. While hemp seeds and hemp oil have been touted for their omegas, CBD oil has little know nutritional value beyond its high antioxidant profile (which can help your body fight off free radicals, help you defend yourself against certain illnesses, and support healthy brain activity). That said, CBD is now required to be registered as a novel food in the UK, which could help thrust nutritional research forward. For the sake of this discussion, it is worth noting that CBD is generally combined with a carrier oil like olive oil, coconut oil, or hemp seed oil; which are loaded with ‘good fats’ that are essential to your diet. Just don’t overdo it if you want to maintain a healthy weight. 4. CBD can be incorporated into your exercise regime Then there is exercise to tie it all in together. For starters, preliminary research has suggested that CBD possesses anti-inflammatory activity, which could affect exercise-induced inflammation and related pain. So if this is true, you can certainly use CBD as part of your exercise recovery regime to discourage delayed onset muscle soreness (DOMS) or the likes. So if you need to get moving, CBD might just be your best friend. It goes without saying, if you have any concerns about CBD’s effects on your body, speak to a healthcare provider. What is CBD oil CBD oil is made by extracting cannabidiol from the Cannabis sativa L. industrial hemp plant. CBD oil that is extracted from hemp contains, by law, less than 0.2% tetrahydrocannabinol (THC), the psychoactive component of cannabis. This means it won’t get you high. It is then blended with a carrier that then “carries” the medicinal properties, allowing them to be retained, easily spread, and even enhanced. Carriers include alcohol, or oils like coconut, olive, jojoba, grapeseed and sweet almond. A comparison of CBD oils: Why it matters legally? There are different types of CBD oil. The choice you make matters, particularly from a legal perspective. Full-spectrum CBD oil Full-spectrum CBD oil contains a range of compounds, including THC. While THC is regulated under UK law, many products inadvertently contain higher than legal levels. This can result in a positive THC drug test, loss of license, or a criminal record. Broad-spectrum CBD oil Broad-spectrum CBD oil contains a range of compounds, but no THC. This type of CBD is popular with users who want to take advantage of the additional compounds besides CBD in the plant, but do not want the psychoactive effects of THC. CBD isolate CBD isolate oil contains CBD-only. The absence of THC ensures you gain CBD’s health benefits without exposure to THC. This is the option we at Cannabotech incorporate so we can provide you with our Pure CBD Guarantee! Tip: If you’re unsure how to gain the remarkable benefits of CBD and remain legally compliant, we recommend you read our article, CBD Laws In The Uk: What You Need To Know Before You Purchase CBD? How can you easily integrate CBD for wellness routine success? Wonderfully, there is a range of choices. Thanks to modern technology and scientific blending, CBD comes in a variety of products. Here’s what to expect on the shelves. CBD ingestibles, consumables, ediblesCBD powderCBD teaCBD tinctures or dropsCBD oilsCBD skincare products including creams, lotions, serums, cleansersCBD topicals including ointments, balms, and creams CBD topicals CBD topicals are health and wellness faves due to their easy application and efficacy. Cannabotech’s topical line offers advanced solutions for today’s common skin complaints such as dry, red, itchy skin using scientifically proven ingredients that benefit the skin including medicinal mushrooms, CBD, and botanical ingredients. These plant-based products are suitable for sensitive skin and people who may be prone to psoriasis. In addition, we have developed a formula to help cool tired and tight muscles. This is the next generation of topical formulations. CBD skincare products CBD has become one of the hottest trends in skincare, particularly among the 30+ crowd concerned about premature ageing. Yes, UV rays can damage your precious skin even in the London fog. Cannabotech’s skincare line offers advanced solutions for today’s environmental stressors on the skin that cause premature ageing using a combination of medicinal mushrooms, CBD, and other botanical ingredients. These antioxidant-rich, ultra-hydrating formulations can help the skin fight free radicals, the sun’s harmful rays, pollution, and more with a protective skin barrier to promote radiant skin. CBD food supplements Cannabotech’s offers specialist food supplements that contain medicinal mushrooms and premium CBD alongside authorised botanical ingredients or essential vitamins to support modern health concerns including sleep, stress, energy, ageing, liver function, heart function, glucose levels, and more. Our supplements are currently available in liquid drops. Stay tuned for our upcoming tablets too! As with any new health and wellness routine, it is important that you speak to a trained healthcare professional if you have a specific condition you are managing. Choose the right CBD concentration and dosage for you We are each unique, as are our bodies and the way we respond to nature’s compounds. So, as with all nutritional supplements, trial and error may be required. The way you take or apply CBD also matters, as does the health challenge you wish to relieve. As a general rule, start with a small dose and work up to find the right amount for you. For internal use, the Food Standards Agency (FSA) advises healthy adults to take up to 28 drops a day of a 5% CBD ( 70 mg) unless recommended otherwise by your doctor.For external use, we suggest working starting with about the size of a pence for a small area (Just enough to rub in smoothly without leaving a thick film in the area of concern). Remember, it is best to speak to a healthcare provider if you are concerned about a specific condition. The CBD for wellness routine takeaway Growing insight into the many benefits of CBD has led to an overdue revolution. People are incorporating cannabidiol in their wellness routine en masse. Is it time you join this road to health and wellness too?
How CBD and the Thyroid Are Related: Medications and Disorders
Cbd discussionsHow CBD and the Thyroid Are Related: Medications and DisordersThe thyroid is an endocrine gland that is responsible for producing hormones that regulate the body's metabolic rate, brain development, and bone maintenance. As with all bodily systems, the thyroid can break down and function poorly, thus needing medical influence to prevent the associated danger. The thyroid contains a number of cannabinoid receptors (CB1 and CB2), which is the reason for individuals claiming that cannabidiol (CBD) can be used as a treatment of various thyroid conditions. In this article, we will break down the potential for this effectiveness, as well as touch on the interactions between CBD and thyroid medications. Why People Take Thyroid Medication Although there are many different thyroid conditions, all of them contribute to one of two main types of thyroid disease: hypothyroidism and hyperthyroidism, which are simply defined by the thyroid producing the wrong amount of hormones. Hypothyroidism Occurs when the thyroid produces too little hormones, and can be caused by a number of factors including, but not limited to: ThyroiditisHashitomo's DiseaseIodine deficiency Reduced hormone production can lead to the following symptoms, among others: FatigueWeight gainHeavy and frequent menstruationDry skin and hair Although the sub-conditions that lead to hypothyroidism can sometimes be treated, there is also a general treatment that involves replacing the missing hormones with a medication called levothyroxine. » Hydrate your skin with CBD-based Soothe Skin Balm by Cannabotech Hyperthyroidism Occurs when the thyroid produces too many hormones, and can be caused by a number of factors including, but not limited to: ThyroiditisGraves' DiseaseExcessive iodine Increased hormone production can lead to the following symptoms, among others: AnxietyWeight-lossInsomniaMuscle weakness » Beat insomnia with CBD, check out our Beauty Sleep Drops Hyperthyroidism can be treated in a number of ways, such as with a medication called methimazole (Tapazole) or Propylthiouracil that restricts the thyroid from producing excess hormones. Does CBD Interfere With or Affect Thyroid Medication? Currently, there is no scientific evidence to verify whether there are interactions between CBD, levothyroxine, and other thyroid medications. However, some assumptions can be drawn based on the scientific knowledge we have about interactions between CBD and other medications. Firstly, both CBD and most thyroid medications are metabolised by the same enzymes, and so taking them simultaneously would result in them having to compete for metabolism and thus lower the effectiveness of both. Secondly, taking CBD together with other medications sometimes results in a potential increase in side effects experienced as a result of the medication. There is anecdotal evidence to suggest that the side effects of taking the substances together would be relatively low, but should still be separated by a few hours and monitored closely. CBD as a Standalone Treatment: A Final Thought The short answer to CBD oil's effectiveness as a treatment for hyper or hypothyroidism is that more research is needed. However, there is some scientific evidence to suggest the efficacy of using CBD products to treat certain symptoms associated with thyroid conditions, namely: CBD oils or tinctures can potentially help decrease the inflammation and pain caused by a problematic thyroid, as well as potentially alleviate the associated anxiety and depression.CBD balms can be applied topically to alleviate skin and hair conditions. Although there is hope that CBD can help in regulating a functioning thyroid and alleviating the symptoms caused by problematic ones, you should always consult with your doctor before trying to fix serious medical conditions on your own.
Taking CBD for Diabetes: What You Need to Know
Cbd discussionsTaking CBD for Diabetes: What You Need to KnowDiabetes is a condition that impairs the body's ability to produce or respond to insulin, which leads to excess glucose in the blood and abnormal metabolism of carbohydrates. The difference between type 1 and type 2 diabetes is that type 1 diabetes is genetic and is usually identified early on in life, whereas type 2 diabetes is brought on by poor dietary habits for a prolonged period. There is no known cure for diabetes, but there are treatments to manage and control the symptoms so that diabetic patients can live mostly normal lives and even go into remission. That being said, is there any benefit to using CBD oil to assist other diabetes treatments? Read on to find out. Benefits of CBD for Diabetes As it turns out, there are various preventative and therapeutic benefits of using CBD for diabetes. 1. CBD May Lower Diabetes Risk A small study carried out on non-obese diabetic rats found that they showed a significantly lower risk of developing diabetes when treated with CBD oil than those who weren't. Although this is a promising result, there is nowhere near enough evidence or research on this topic to draw definitive conclusions. 2. CBD May Have Analgesic Properties One of the symptoms of diabetes is diabetic neuropathy—otherwise known as diabetic nerve pain—which affects your nerves and sends confused signals to your hands and feet that your brain can interpret as: Numbness or tingling in your extremetiesBurning or aching pain Studies have shown that CBD has pain-relieving (analgesic) properties that could lessen these diabetic symptoms. 3. CBD May Have Anti-inflammatory Properties Another symptom of high blood sugar is build-up of inflammation, which increases your risk of: Heart diseaseCancerRheumatoid arthritis Inflammation can even worsen the progression of diabetes. Interestingly, research has been conducted on the effect of CBD on inflammation caused specifically by elevated blood sugar levels and found that it appears to reduce this inflammation build-up significantly. 4. CBD Has Stress-Relieving Properties The debilitating effects of stress on the mind and body are well-known as it stands, and research has even shown that it can potentially worsen the effects of diabetes, such as hyperglycemia (high blood sugar). As discussed in our article, CBD Oil and Medicinal Mushrooms for Anxiety and Stress Relief, CBD appears to have potent stress-relieving capabilities. Safety of Using CBD for Diabetes For the most part, the risk of side effects from taking CBD is relatively low, but could they be more lethal if used by diabetics? The side effects that are most often reported from CBD use include: Somnolence (drowsiness or fatigue)Reduced appetiteDiarrhoeaDry mouth Almost none of these side effects are related to symptoms of diabetes, and so it is highly unlikely that CBD can worsen the effect of diabetes. However, there are two potential causes for concern: the risk of interactions between CBD and diabetes medication and the impurity of many CBD products. Does CBD Interact With Diabetes Medication? CBD has been observed to have drug-drug interactions with many pharmaceuticals due to the fact that it inhibits many of the same enzymes used to metabolise those prescription drugs. This runs the risk of reducing the effectiveness of the CBD and the drug as well as increasing the risk and severity of side effects. As such, it is important to space out your doses of medication and CBD by at least four hours to reduce these risks. Impurity of CBD Products Currently, manufacturing of CBD products is not regulated in many parts of the world, which has resulted in fraudulent claims on the labels of many CBD products that actually contain vastly different concentrations of all present cannabinoids, including CBD and THC (the psychoactive cannabinoid found in cannabis). This is why it is essential to always purchase your CBD from reputable sources that can back their claims with 3rd-party lab results. How to Use CBD for Diabetes Although there are many different forms of CBD that all offer different advantages and disadvantages, dealing with chronic conditions like diabetes is going to require the best possible type of CBD product. As such, you should avoid topicals—as they have the lowest bioavailability—and inhaled products—as these can potentially damage your lungs and airways. Instead make use of edibles that have the longest duration of effect, or tinctures applied sublingually as they have the best balance of bioavailability, speed of effect, and duration of effect. Additionally, the beneficial effects of CBD may be increased when used in conjunction with other therapeutic components that offer similar benefits. The medicinal properties of functional mushrooms are increasing in popularity as more research is being conducted, and many of them appear to offer the same anti-inflammatory and blood sugar-modulating properties of CBD. To learn more, read our posts about the benefits of the following mushrooms: Turkey TailCordycepsChagaMaitakeReishiLion's Mane For specific products that combine the benefits of CBD, medicinal mushrooms, and many other therapeutic components, visit our online store. Just be sure to always check with your doctor as many medicinal mushroom species seem to have hypoglycemic (blood sugar-reducing) properties that could be dangerous if taken in conjunction with other diabetes medication.
Holistic Treatments for Polymyalgia Rheumatica (CBD Oil and Others)
Cbd discussionsHolistic Treatments for Polymyalgia Rheumatica (CBD Oil and Others)Polymyalgia Rheumatica (PMR) is categorised as an inflammatory condition that leads to joint pain and stiffness, commonly affecting individuals older than 50. It is difficult to diagnose, and currently impossible to cure. The best pharmaceutical treatments for the condition involve combating the symptoms with low-dose corticosteroids, which is problematic as long-term use of corticosteroids can lead to osteoporosis. Recently, individuals are turning to various alternative treatments and natural remedies in an attempt to help symptoms of PMR holistically, which will be covered in this article. What are the Best Pain-Relief Treatments for Polymyalgia Rheumatica? Choose a Healthy Diet Although a healthy diet may not fix the problem outright, certain foods can definitely worsen the symptoms of PMR. When choosing what foods you should eat, consider sticking to the following guidelines: Anti-Inflammatory Foods such as nuts, fruits, leafy greens, whole grains, and green tea can contribute to a decrease in inflammation throughout the body.Foods rich in Calcium and Vitamin D, such as soybeans, spinach, cheese, fatty fish, eggs, and mushrooms can help maintain good bone health and counter the negative effect of steroids and corticosteroid medicines.Omega-3 Fatty Acids obtained from fish, seeds, and leafy greens can help counteract the immune system's further production of inflammation. In addition to these, you should stay away from foods that are deep-fried or contain poor-quality vegetable oils, refined carbohydrates and sugars, alcohol, and red meats. Take Supplements If certain foods are unattainable, they can be replaced with supplements in order to give your body the necessary nutrients that it needs. Consider Alternative Medicines Traditional Chinese Medicines have been reported to have varying effects in the holistic treatment of rheumatic conditions. Corydalis (Yu Jin) contains a pain-relieving compound called dehydrocorybulbine (DHCB), and Curcumae (Jiang Huang) has been noted to reduce chronic inflammation.Chinese massages have been known to free up stiff and sore shoulders (a common symptom of PMR), promote vigour and strength, and soothe pain.Acupuncture has been associated with relieving pains associated with arthritic and rheumatic conditions. Using CBD Oil for Polymyalgia Rheumatica Although CBD oil may not directly treat PMR, certain products can help with certain symptoms as there is scientific evidence to support the theory that CBD has anti-inflammatory and pain-relieving properties. CBD oils and tinctures can be taken to reduce general inflammation throughout the body over a longer period.CBD balms and creams can be applied topically to particularly inflamed or painful areas. Can CBD Be Taken in Conjunction With Corticosteroids (Prednisone)? CBD interacts with many drugs, and, unfortunately, corticosteroids are one of the most prominently noted. CBD and prednisone both are potent inhibitors of the cytochrome P450 enzyme CYP3A. Taking them in conjunction could lead to a decrease in the clearance of the corticosteroid, which is a measurement of the volume of plasma from which a substance is completely removed per unit time. This interaction is potentially dangerous as it could lead to increased side effects from prednisone, namely, among others: Weight gainMuscle weaknessLower resistance to infectionOsteoporosisAn onset of, or worsening of, diabetes and hypertension. A Final Thought: Can CBD Oil Replace Prednisone? Due to the potential for increased side effects, it is not advised that CBD oil and prednisone be taken in conjunction with one another. Since corticosteroids have the potential to cause osteoporosis in the long term, CBD may be considered as a potential replacement in the future, but there is currently no scientific evidence to support this theory. What this means for you is that you should consult directly with your doctor before deciding to end your medication as they can give you more insight and advice on the topic.
Will Using CBD Oil Help for Ear-Ringing Tinnitus
Cbd discussionsWill Using CBD Oil Help for Ear-Ringing TinnitusCannabidiol (CBD) is becoming something of a buzzword in recent years, with individuals strongly advocating its effectiveness in treating everything from mental disorders to chronic pain. Now there are even those who claim that it can treat symptoms of tinnitus (an annoying condition associated with persistent noise in the ears) as well, but how true is this statement? Can CBD Help With Tinnitus? As to why people claim that CBD can alleviate tinnitus, there are two popular working theories: Cannabinoid Receptors Among other things, CBD interacts with two types of receptors in the human body, commonly referred to as CB1 and CB2 receptors. Emerging research suggests that these receptors may play a role in auditory perception and that some forms of tinnitus exist as a result of hyperactivity in these receptors. CBD is also associated with modulating γ-aminobutyric acid (GABA) levels, which is an inhibitory neurotransmitter in the brain that blocks certain brain signals. It is believed that CBD does affect GABA levels positively. The way in which CBD interacts with this neurotransmitter and cannabinoid receptors is one of the reasons for the belief in its ability to relieve tinnitus, as some scientists claim that it can normalise the hyperactivity associated with tinnitus. However, there is no conclusive evidence of this. Anti-Epileptic Potential Another working theory is that some scientists believe tinnitus to be a form of sensory epilepsy. A number of studies suggest that CBD may exhibit anti-epileptic potential. In fact, it was this property that essentially caused the beginning of research into the medical benefits of CBD as a group of experimental parents discovered that the compound had a therapeutic effect on their children who suffered from a rare form of drug-resistant epilepsy called Dravet syndrome. The relationship between CBD's anti-epileptic potential and the belief that tinnitus is a form of sensory epilepsy explains why some individuals claim its therapeutic effects. However, this is purely anecdotal. What Research Suggests About CBD for Tinnitus Despite the increasingly prominent belief that CBD can relieve symptoms of tinnitus, there is actually a growing body of evidence to suggest otherwise. Although the limited research on this topic has only been carried out in rat models and not on humans, several studies have found that exposing rats to cannabinoids after acoustic trauma actually increased the number of rats displaying tinnitus-like symptoms. What this suggests is the potential for cannabinoids to actually exacerbate tinnitus, instead of alleviating it. Additionally, almost all the evidence of cannabis ameliorating symptoms of tinnitus is purely anecdotal. A Final Thought With how limited the body of research is on this topic, and the different causes of tinnitus and the forms in which it can manifest, it is neither reasonable nor advised to attempt to use CBD to combat symptoms of the condition. In fact, doing so without consulting a doctor beforehand could actually worsen the symptoms.
Can You Effectively Use CBD for COPD?
Cbd discussionsCan You Effectively Use CBD for COPD?Chronic obstructive pulmonary disease (COPD) is a type of long-term lung disease that can cause other disabilities and potentially early death. It is sometimes referred to as emphysema or chronic bronchitis. Though it may be incurable, it is treatable and often preventable. Since it is characterised by inflammation of the airways in the throat and lungs, there are those who believe that various CBD and cannabis oils can be used to assist in the treatment of COPD. When deciding whether or not you should take CBD oil to help with COPD, there are many things you have to take into account. As with all conditions and CBD products, you have to consider the method of application and the dosage, among other factors. While there may not be a definitive yes or no answer for such a complicated topic, there are some principles you can use to help you make your decision. Does CBD Oil Help COPD and Lung Disease? While there might be no concrete evidence that the use of CBD products - either ingested, inhaled, or topically applied - can directly treat COPD, there may be some other potential benefits. CBD May Exhibit Anti-Inflammatory Properties There is a fair amount of scientific evidence to suggest that CBD can reduce general inflammation throughout the body. One of the symptoms of COPD is a respiratory infection that causes an excess build-up of inflammation in the airways. This leads to increased coughing, which causes even further build-up of inflammation. This inflammation doesn't decrease naturally, and so one of the treatments for COPD is anti-inflammatory drugs. As such, adding CBD or cannabis oil to other COPD treatments could strengthen the body's ability to break down inflammation and help the condition become more manageable. CBD May Act as an Analgesic There is some scientific evidence to suggest that CBD may also exhibit analgesic (pain-relieving) properties in certain circumstances. Although the evidence of this alone isn't enough to advocate for the treatment of COPD with CBD, it may be a potential secondary benefit in certain individuals. CBD May Cause Vasodilation Some studies also suggest that CBD may operate as a broncho-and-vaso-dilator, relaxing the airways and blood vessels to potentially reduce blood pressure and make breathing easier. Using CBD Oil for COPD and Lung Disease Even though the inherent benefits of CBD don't change that much across the different methods of application, there are some that could have more potential adverse reactions than others. Since the nature of COPD is that of lung disease or respiratory infection, it is clear that certain methods of CBD use would be more beneficial than others. In addition, it's important to understand that it may not necessarily be feasible to treat COPD with CBD alone, but rather that there may be more benefit in adding CBD to existing COPD treatments. Why You Shouldn't Inhale CBD for COPD Even though there is some anecdotal evidence to support the belief that inhaling CBD - either by vaping the e-juices or smoking the buds - might reduce respiratory issues in the short term, the potential disadvantages far outweigh these benefits. Inhaling anything other than air can aggravate the throat and lungs and lead to an increase in inflammation, and the potential for coughing could even further exacerbate this. There is also debate in the CBD community about a potential CBD solution for a nebulizer or diffuser, but this should also be avoided. Nebulizers work by converting liquid medication into fine droplets (aerosol spray) that can be easily inhaled. CBD oil, which is hydrophobic in nature, would therefore not be as effective as other medications when taken in this manner. In addition, CBD that exists in an alcohol-based solution could aggravate and damage the lungs when inhaled through a nebulizer. Using CBD Tinctures, Oils, and Edibles for COPD The main benefit to using any of these CBD products is the fact that the duration of effects is much longer than other methods, with little variation in their consumption. CBD "tincture" and "oil" are often used interchangeably, but they are actually different products. In oils, CBD is extracted using carbon dioxide, while in tinctures, CBD is extracted in an alcohol-based solution. CBD oils are generally more potent than tinctures, while tinctures generally have a longer shelf-life. Despite their differences, both products can be taken sublingually, which means holding the solution under your tongue for at least 30 seconds to allow the CBD to diffuse through the tissue and into your bloodstream. This allows for the fastest onset of effects (excluding inhalation) as well as a relatively high bioavailability compared to other methods. CBD edibles, on the other hand, can be anything from cookies to gummies that have CBD oil incorporated into them. Although this method utilises your body's metabolism (and therefore has the longest-lasting effect), they also have a comparatively lower bioavailability than CBD taken sublingually. The benefit to edibles is that some individuals may be averse to the taste or texture of oils and tinctures. Can Topical CBD Oils Relieve COPD? CBD topicals, be it creams, lotions, or oils, are simply topical products that have CBD oil mixed into them. They can be applied externally, whereupon the CBD will diffuse through the skin and into the bloodstream. In truth, topical application has the lowest bioavailability of all methods but could be added to other COPD treatments to potentially reduce inflammation in a localised area. In Conclusion Although there is much debate over whether or not CBD products can assist in dealing with symptoms of COPD, there is a relatively low risk associated, so you might as well give it a shot. As long as you choose a method that won't aggravate the lungs, and you start with a low dosage and work your way up slowly, you should be safe to start the process of figuring out the combination that works for you. That being said, you should always check with your doctor before starting as they could give you some more insight, especially if you are on other medications.
Full-Spectrum CBD: What Is It, Benefits, Legality, & More
Cbd discussionsFull-Spectrum CBD: What Is It, Benefits, Legality, & More Cannabidiol (CBD) is a non-psychoactive phytocannabinoid found in the cannabis plant. It has been gaining popularity in recent years as a supposedly effective way of treating many different physical and mental conditions. However, the different types of CBD products differ dramatically in their manufacturing process. Depending on the method you'll choose to utilise your CBD (tinctures, topicals, inhaled products, etc.), all potential products will fall under one of three main categories: Full-spectrum, broad-spectrum, and isolates. They all differ in the compounds they incorporate and, therefore, in the strength of their benefits. In this article, we'll be discussing full-spectrum CBD products and how they differ from other types in their benefits, effects, legality, and more. What Is Full-Spectrum CBD? Full-spectrum CBD is the most complete and unprocessed form of CBD you can purchase. Even though the main focus of CBD oils is the cannabidiol, they actually contain varying amounts of the 80-100 other cannabinoids and over 300 non-cannabinoid components. When CBD products are made, cannabinoids are extracted from the raw plant. The degree of processing is what determines the type of product you're going to end up with. Full-spectrum products have the least processing, meaning that the final product will have the most available cannabinoids than any other product, including psychoactive tetrahydrocannabinol (THC), though not enough to give you the "high" feeling associated with marijuana. Benefits of Full-Spectrum CBD The inherent benefits of CBD as a substance don't vary dramatically between different CBD products. For a complete list of what CBD can do, read our post: CBD Benefits: How This Natural Compound Promotes Health and Wellness. That being said, there are some other benefits presented by full-spectrum hemp extracts, such as: The entourage effect Research has shown that the beneficial effects of cannabinoids can actually be enhanced by the presence of other cannabinoids in something called the "entourage effect." This means that full-spectrum CBD, with the most present cannabinoids and terpenes, has a more potent effect than individual cannabinoids. More natural Less processing means less chance of unhealthy and dangerous chemicals finding their way into the final product. Risks of Full-Spectrum CBD Despite the supposed benefits of full-spectrum CBD oil, it is not without risk, the most prominent of which are as follows: Cannabinoid sensitivity Some people may be perfectly fine to take CBD as an isolated substance, but that doesn't necessarily mean that they will react well to the numerous other cannabinoids and terpenes in the cannabis plant. Poor reactions to specific cannabinoids can cause anything from hives to breathing problems. THC presence Though there shouldn't be enough THC in a CBD product to get you high, it could be enough to cause a failed drug test or, in extreme cases, exacerbate symptoms of anxiety or other psychiatric conditions. Legality of Full-Spectrum CBD Although CBD is legal in the UK, its psychoactive cousin (THC) is not. Since full-spectrum CBD does contain trace amounts of THC, what does that mean for their legality? The short answer is that it's different per country. However, most places that still restrict THC allow for its presence in CBD products as long as it is in small doses. Most laws, including the current 2022 UK laws, usually have a solid number of 0.2% being the maximum concentration of THC allowed. This is some cause for concern as recent studies have found that many so-called "legal" full-spectrum products in the United States contain 0.3% THC or more (sometimes reaching up to 40%). Even more dangerous is the fact that THC, even in doses as small as that, can still show up on drug tests that are searching for it. The potential for this depends on a lot of factors such as quantity, frequency of use, and your body's metabolism. If you're a frequent user of products containing THC, the substance can show up in your urine up to a month after you stop. Furthermore, there are no requirements for CBD distributors to provide proof of what's in their products, which is why you should always buy from reputable sources that can provide 3rd-party lab results to validate their claims. Other Types of CBD: Broad-Spectrum and Isolates Aside from full-spectrum CBD, there are two more CBD products that you can purchase that differ from it. Broad-Spectrum CBD Broad-spectrum CBD is similar to full-spectrum in that it contains various cannabinoids, terpenes, and other components aside from just cannabidiol, but less so than typical full-spectrum products. Though the extraction processes are similar to full-spectrum, broad-spectrum is a more refined product. Typically (but not always), the THC is removed from broad-spectrum products along with some of the riskier components. In general, broad-spectrum CBD is safer than full-spectrum CBD but still manages to utilise many of the benefits that come from the entourage effect. CBD Isolate Isolates are the most processed and refined CBD products that have every other cannabinoid, terpene, flavonoid, and other compounds aside from CBD chemically removed until you are left with the purest form of CBD, making this type of product a more expensive variation. As explained earlier, removing the other compounds from the finished product may reduce the effectiveness of the CBD. However, this can be a suitable product for those who still want to experience some of the benefits of CBD but are worried about or sensitive to the other compounds found in the cannabis plant. Is Full-Spectrum CBD Right for You? There is no strict guide to determine what CBD product is best for you, but there are some basic principles you can start with. If you aren't sensitive to THC and other cannabinoids and want to get the most benefit out of the oil, opt for full-spectrum or broad-spectrum products. However, if you work in a very conservative field of work (such as law or police work), or think you might be drug tested at some point, consider opting for 3rd-party validated broad-spectrum with zero THC or isolates instead. Finally, if you're new to the CBD world and just want to get a taste of what it can do for you with the lowest possible risk, start with an isolate and work your way up from there.